§02 Research · the work

Publications,
posters,
and the science.

§02 All work n = 7
Culturing CAR-T cells under hypoxic and hyperbaric conditions yields increased proliferation and functional potency without changes in phenotype.
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poster [2025]
Culturing CAR-T cells under hypoxic and hyperbaric conditions yields increased proliferation and functional potency without changes in phenotype.
Massi E, Garcia C, Lemar H, Bronevetsky Y, Eaker S, Lim J.
ISCT Annual Meeting · New Orleans, LA
Modulating Environmental Conditions to Enhance Production of Potent Cell Therapies for the Solid Tumor Microenvironment.
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poster [2024]
Modulating Environmental Conditions to Enhance Production of Potent Cell Therapies for the Solid Tumor Microenvironment.
Garcia C, Massi E, Lemar H, Bronevetsky Y, Eaker S, Lim J.
ISCT Annual Meeting · Vancouver, Canada

[2024]
CD19 CAR T manufactured under TME culture conditions exhibit superior potency & persistence.
Massi E, Bronevetsky Y, Garcia C, Le L, Lemar H, Eaker S, Lim J.
Xcell Biosciences
app note
[2021]
Recurrent Mutations in Cyclin D3 Confer Clinical Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia.
Smith CC, Viny AD, Massi E, Kandoth C, Socci ND, Rapaport F, Najm M, Medina-Martinez JS, Papaemmanuil E, Tarver TC, Hsu HH, Le MH, West B, Bollag G, Taylor BS, Levine RL, Shah NP.
Clin Cancer Res.
publication
[2017]
Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysis.
Smith CC, Paguirigan A, Jeschke GR, Lin KC, Massi E, Tarver T, Chin CS, Asthana S, Olshen A, Travers KJ, Wang S, Levis MJ, Perl AE, Radich JP, Shah NP.
Blood.
publication
[2015]
Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397.
Smith CC, Zhang C, Lin KC, Lasater EA, Zhang Y, Massi E, Damon LE, Pendleton M, Bashir A, Sebra R, Perl A, Kasarskis A, Shellooe R, Tsang G, Carias H, Powell B, Burton EA, Matusow B, Zhang J, Spevak W, Ibrahim PN, Le MH, Hsu HH, Habets G, West BL, Bollag G, Shah NP.
Cancer Discov.
publication
[2012]
Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.
Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, Sanders RW, Moore JP.
J Biol Chem.
publication